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This brief on implementation guidance provides country level stakeholders including government officials, regional/district managers and service providers to develop a more integrated approach to quality planning, improvement and control, harmonization of multiple efforts; and use of a learning system to demonstrate, implement and scale up the quality of care in the health system. The Implementation Guidance also outlines a systematic process for building both institutional and clinical capabilities to support the implementation, scale up and sustainability of quality of care, at national, district and health-facility levels.